The Breath That Moves Us

US moves to improve health decisions.

XMAP215: A Tip Tracker that Really Moves

XMAP215 is a microtubule plus-end binding protein implicated in modulating microtubule dynamics. In this issue, Brouhard et al. (2008) propose a new mechanism to explain how XMAP215 promotes microtubule growth. They report that XMAP215 moves with the growing microtubule plus ends where it catalyzes the addition of tubulin subunits.

The headaches that awaken us.

CLINICAL HISTORY A 56-year-old male with a history of wellcontrolled hypertension and episodic tension-type headache has been awoken from sleep 3 nights per month for the last 2 years between 1:00 a.m. and 2:30 a.m. with a moderately severe bifrontal pressing headache that persists for 1 to 2 hours untreated and 10 minutes if treated with a caffeine containing overthe-counter analgesic. Questio...

O-12: Tubulin Reversible Acetylation – Driving The Moves and The Moves Behind The Drive

Background Asthenozoospermia accounts for almost 50% of the cases of male infertility. Our study investigating phosphoproteins differentially expressed in asthenozoosperm has identified the phosphoproteins relevant to sperm motility and the signature molecules likely to be altered in asthenozoospermia. The 66 phosphoproteins differentially expressed included four alpha tubulin isoforms which we...

I-16: Tubulin Reversible Acetylation – Driving The Moves and The Moves Behind The Drive

Background Asthenozoospermia accounts for almost 50% of the cases of male infertility. Our study investigating phosphoproteins differentially expressed in asthenozoosperm has identified the phosphoproteins relevant to sperm motility and the signature molecules likely to be altered in asthenozoospermia. The 66 phosphoproteins differentially expressed included four alpha tubulin isoforms which we...